Antimicrobial peptides (AMPs), such as cathelicidins and defensins, play crucial roles in the gastrointestinal (GI) tract as host defence peptides. The book “Antimicrobial Peptides in Gastrointestinal Diseases” delves into the physiological functions and pharmacological actions of AMPs in various conditions affecting the GI tract, including inflammation, cancer, and infections. From fundamental research to practical clinical applications for GI diseases, this book offers comprehensive coverage. The ongoing research and advancements in AMPs pave the way for further exploration of these peptides, not only in GI diseases but also in similar conditions affecting other organs. AMPs are essential for regulating the human microbiome and serving as a second line of defence in the GI mucosa. They help prevent pathogen colonization, modulate the innate response to invading pathogens, and influence immunological reactions during inflammatory processes and oncogenic development in the GI mucosa.

Most importantly, AMPs exhibit diverse antimicrobial properties against various infectious diseases in the GI tract. Given their physiological functions and pharmacological actions, AMPs show great promise as therapeutic agents for treating inflammation, cancer, and infections in the GI tract. This book provides a comprehensive overview of AMPs, focusing on cathelicidin and defensin, in different diseases. It covers topics such as inflammation, ulcer repair in the stomach and colon, and carcinogenesis in the GI tract. The information on AMPs is presented concisely, offering valuable insights into all aspects of these peptides. Furthermore, it encourages further research on AMPs and their development as drugs, from laboratory experiments to clinical applications.

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