Rhabdoviruses and Filoviruses are types of RNA viruses that have a single-stranded, non-segmented, negative-strand genome. These viruses are known to cause significant illness and death in both humans and animals. Some members of these virus families have been extensively studied and have served as valuable models for understanding viral replication, host responses to infection, and strategies used by the viruses to counteract the host’s defenses. Rhabdoviruses have also been utilized as vaccine carriers and oncolytic agents.
Recent studies on Filoviruses have provided important insights into how these viruses enter susceptible cells, replicate, cause disease, and evade the immune system of the host. This book focuses on the latest discoveries regarding the structure of Rhabdoviruses and Filoviruses, their replication mechanisms, how host cells respond to viral infections, and the strategies employed by the viruses to counteract the host’s immune defenses. Additionally, the book includes chapters on emerging viruses and therapeutic approaches for intervention.
This authoritative text compiles the most recent advancements in the cellular and molecular biology of Rhabdo- and Filoviruses, shedding light on the mechanisms underlying their pathogenesis.
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