The advent of antibiotics during the early 20th century brought about a profound revolution in both human and veterinary medicine. These powerful medications now play a crucial role in saving countless lives annually, not only in the United States but also across the globe. Nevertheless, the emergence of antibiotic-resistant bacterial strains poses a grave menace to public health and the economy. If the efficacy of antibiotics, which are drugs designed to eliminate or impede the growth of bacteria, diminishes, our ability to effectively and swiftly treat bacterial infections, including those causing pneumonia, foodborne illnesses, and healthcare-associated infections, will be compromised. As an increasing number of bacterial strains develop resistance to a growing array of antibiotics, our options for effective drugs have become progressively limited, more costly, and, in some instances, non-existent. In a world where effective antibiotics are scarce, modern medical advancements like surgeries, transplants, and chemotherapy may no longer be feasible due to the constant threat of infection. This publication outlines the national strategy and action plan aimed at combating antibiotic-resistant bacteria.

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